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Optimal Calcium Intake National Institutes of Health Consensus Development Conference Statement
June 6-8, 1994
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Calcium and Health: Part 1 Calcium and Health: Part 2
Calcium and Health: Part 3
Calcium and Health: Part 4 Calcium and Health: Part 5
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Part 2
Introduction
It has been a decade since
the 1984 Consensus Development Conference on Osteoporosis first suggested that increased intake
of calcium might help prevent osteoporosis. Osteoporosis affects more than 25 million people
in the United States and is the major underlying cause of bone fractures in postmenopausal women
and the elderly.
Previous surveys have revealed that the U.S. population experiences more than
1.5 million fractures annually at a cost in excess of $10 billion per year to the health care
system. Two important factors that influence the occurrence of osteoporosis are optimal peak
bone mass attained in the first two to three decades of life and the rate at which bone is lost
in later years. Adequate calcium intake is critical to achieving optimal peak bone mass and
modifies the rate of bone loss associated with aging.
A number of publications have addressed the possible role of calcium intake in the prevention
of disorders other than osteoporosis, including other bone diseases, oral bone loss, hypertension,
and preeclampsia, a hypertensive disorder of pregnancy. The results of recent research investigating
these issues indicate that the optimal amount of calcium intake may be greater than the amount
consumed by most Americans. At the same time, the general public and scientists have been exposed
to a body of information emphasizing the value of ensuring adequate calcium intake throughout
life.
Calcium
is an essential nutrient. Optimal calcium intake may vary according to a person's age, sex,
and ethnicity. Other factors play a role in calcium intake, including vitamin D, which is needed
for adequate calcium absorption. Many factors can negatively influence calcium availability,
such as certain medications or food components. Optimal calcium intake may be achieved through
diet, calcium-fortified foods, calcium supplements, or various combinations of these.
In view
of the great public interest in nutrition and disease prevention, the scientific community has
an obligation to integrate new data and to provide health care practitioners and the public
with guidance, even though all of the necessary long-term studies may not have been completed.
In some cases, the new data, however exciting, point to the need for further research rather
than to specific recommendations. Future investigations in this rapidly expanding area of research
will lead undoubtedly to more definitive information, which will provide the basis for new recommendations.
To address issues related to optimal calcium intake, the National Institute of Arthritis and
Musculoskeletal and Skin Diseases together with the Office of Medical Applications of Research
of the National Institutes of Health, convened a Consensus Development Conference on Optimal
Calcium Intake on June 6-8, 1994. The conference was cosponsored by the Office of Research on
Women's Health, Office of the Director; the National Institute on Aging; the National Cancer
Institute; the National Institute of Child Health and Human Development; the National Institute
of Diabetes and Digestive and Kidney Diseases; the National Heart, Lung, and Blood Institute;
and the National Institute of Dental Research, all of the National Institutes of Health. Conference
participants included experts from many different fields, including osteoporosis and bone and
dental health, nursing, dietetics, epidemiology, endocrinology, gastroenterology, nephrology,
rheumatology, oncology, hypertension, nutrition and public education, and biostatistics, as
well as representatives from the public.
After 1-1/2 days of presentations by experts in the
relevant fields and audience discussion, an independent, non-Federal consensus panel weighed
the scientific evidence and formulated a consensus statement in response to the following six
questions: What is the optimal amount of calcium intake? What are the important cofactors for
achieving optimal calcium intake? What are the risks associated with increased levels of calcium
intake? What are the best ways to attain optimal calcium intake? What public health strategies
are available and needed to implement optimal calcium intake recommendations? What are the recommendations
for future research on calcium intake? The consensus panel prepared a draft report summarizing
the evidence pertinent to the key issues regarding optimal calcium intake:
Optimal
Calcium Intake, Part 3
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