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American
Journal of Clinical Nutrition
A recent study published in the American Journal of Clinical Nutrition investigated
calcium intake and risk of colon adenoma. Adenomas are benign growths that are often associated
with early stages of colorectal tumor development. Since previous research has shown that
calcium intake reduces the risk of colorectal tumors, evaluating the association of calcium
intake to the risk of colon adenoma may be useful in the prevention of colorectal cancer.
Calcium Supplement Reduces Risk
The researchers compared the total calcium intake of 3,696 participants with verified
adenoma of the colon with the calcium intake of 34,817 control participants in the Prostate,
Lung, Colorectal, and Ovarian Cancer Screening Trial. After adjustment for known risk factors,
adenoma risk was 12% lower for participants with the highest total calcium intake than for
participants with the lowest calcium intake. The protective association between total calcium
and colorectal adenoma was largely due to calcium supplement use, with a 27% decrease in
adenoma risk for participants taking >1200 mg/d than for nonusers of supplements.
Take Calcium Every Day
High calcium intake, particularly from supplements, is associated with a reduced
risk of colorectal adenoma.
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